SEC
|
Carter Martha J.
|
Chief Regulatory Officer
|
|
-120
|
$43.80
|
-$5.26K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
-1.1K
|
$43.80
|
-$46.30K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-228
|
$43.80
|
-$9.99K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
-102
|
$43.80
|
-$4.47K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-102
|
$43.80
|
-$4.47K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-197
|
$43.80
|
-$8.63K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-102
|
$43.80
|
-$4.47K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
+30K
|
$43.90
|
+$1.33M
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
+53K
|
$43.80
|
+$2.33M
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
+52K
|
$43.80
|
+$2.27M
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-469
|
$19.06
|
-$8.94K
|
|
SEC
|
Carter Martha J.
|
Chief Regulatory Officer
|
|
-104
|
$19.58
|
-$2.04K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
-919
|
$19.58
|
-$17.99K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-656
|
$19.45
|
-$12.76K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
-104
|
$19.58
|
-$2.04K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-104
|
$19.58
|
-$2.04K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-202
|
$19.58
|
-$3.96K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-104
|
$19.58
|
-$2.04K
|
|
SEC
|
EDELMAN JOSEPH
|
N/A
|
|
-420K
|
$22.61
|
-$9.51M
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-80
|
$23.79
|
-$1.90K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-445
|
$19.40
|
-$8.63K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-657
|
$24.21
|
-$15.91K
|
|
SEC
|
Carter Martha J.
|
Chief Regulatory Officer
|
|
-106
|
$24.68
|
-$2.62K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
-929
|
$24.67
|
-$22.92K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
-106
|
$24.67
|
-$2.62K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-106
|
$24.67
|
-$2.62K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-205
|
$24.68
|
-$5.06K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-106
|
$24.67
|
-$2.62K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-95
|
$24.03
|
-$2.28K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-461
|
$19.47
|
-$8.98K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-655
|
$33.22
|
-$21.76K
|
|
SEC
|
Carter Martha J.
|
Chief Regulatory Officer
|
|
-103
|
$32.92
|
-$3.39K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
-907
|
$33.11
|
-$30.03K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
-103
|
$32.92
|
-$3.39K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-103
|
$32.92
|
-$3.39K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-200
|
$32.92
|
-$6.58K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-103
|
$32.92
|
-$3.39K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-96
|
$35.74
|
-$3.43K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-454
|
$30.52
|
-$13.86K
|
|
SEC
|
Carter Martha J.
|
Chief Regulatory Officer
|
|
-423
|
$24.52
|
-$10.37K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
-3.7K
|
$24.88
|
-$91.66K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-1.7K
|
$24.94
|
-$42.10K
|
|
SEC
|
Graham Michelle
|
Chief Human Resources Officer
|
|
-418
|
$24.72
|
-$10.33K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-416
|
$24.88
|
-$10.35K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-808
|
$24.88
|
-$20.10K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-416
|
$24.88
|
-$10.35K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-111
|
$25.95
|
-$2.88K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-474
|
$23.92
|
-$11.34K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-312
|
$29.10
|
-$9.08K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-95
|
$28.83
|
-$2.74K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-93
|
$30.23
|
-$2.81K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-451
|
$32.05
|
-$14.45K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
+4.2K
|
$23.29
|
+$98.12K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-313
|
$32.21
|
-$10.08K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-90
|
$34.13
|
-$3.07K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-98
|
$35.02
|
-$3.43K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-471
|
$36.01
|
-$16.96K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-312
|
$32.16
|
-$10.03K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-90
|
$31.75
|
-$2.86K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-92
|
$32.12
|
-$2.96K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-1.4K
|
$33.58
|
-$47.89K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-422
|
$34.02
|
-$14.36K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
+7.9K
|
$16.94
|
+$133.15K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
+5.4K
|
$0.68
|
+$3.67K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
+5.4K
|
$0.68
|
+$3.67K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-110
|
$37.33
|
-$4.11K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-460
|
$39.07
|
-$17.97K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-89
|
$34.71
|
-$3.09K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-89
|
$34.55
|
-$3.07K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-90
|
$37.30
|
-$3.36K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-451
|
$33.20
|
-$14.97K
|
|
SEC
|
EDELMAN JOSEPH
|
N/A
|
|
+400K
|
$40.00
|
+$16.00M
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-500
|
$35.51
|
-$17.76K
|
|
SEC
|
Mattsson Jan
|
Chief Scientific Officer
|
|
-10K
|
$45.55
|
-$455.50K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-91
|
$25.80
|
-$2.35K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-91
|
$25.80
|
-$2.35K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-92
|
$25.56
|
-$2.35K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-397
|
$30.79
|
-$12.22K
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-92
|
$17.68
|
-$1.63K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-92
|
$17.64
|
-$1.62K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-97
|
$16.52
|
-$1.60K
|
|
SEC
|
Stephenson Pamela
|
Chief Commercial Officer
|
|
-1.8K
|
$17.60
|
-$31.42K
|
|
SEC
|
EDELMAN JOSEPH
|
N/A
|
|
+256K
|
$21.00
|
+$5.37M
|
|
SEC
|
Duncan Jason
|
Chief Legal Officer and GC
|
|
-447
|
$23.97
|
-$10.71K
|
|
SEC
|
Horn Patrick Taylor
|
Chief Medical Officer
|
|
-443
|
$24.29
|
-$10.76K
|
|
SEC
|
Harford Simon N.R.
|
CFO and Treasurer
|
|
-105
|
$27.20
|
-$2.86K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
+1K
|
$25.02
|
+$25.67K
|
|
SEC
|
Cooper Ronald Harold Wilfred
|
President and CEO
|
|
+788
|
$31.85
|
+$25.10K
|
|
SEC
|
Mattsson Jan
|
Chief Operating Officer
|
|
-25K
|
$32.26
|
-$806.50K
|
|
SEC
|
BROWN JULIA R
|
N/A
|
|
+7.8K
|
$9.00
|
+$70.50K
|
|
SEC
|
PHASE4 VENTURES III LP
|
N/A
|
|
-100K
|
$34.44
|
-$3.44M
|
|
SEC
|
EDELMAN JOSEPH
|
N/A
|
|
+275K
|
$33.00
|
+$9.08M
|
|
SEC
|
ASTRAZENECA AB
|
N/A
|
|
-500K
|
$21.40
|
-$10.70M
|
|